Tedatioxetine
As of the edition of 20 October 2026, Tedatioxetine is a small molecule: went quiet in 2009; acts on ADRA1A, HTR2A and HTR2C and 8 more.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Went quiet, 2009
- Kind
- Small molecule
- Registered trials
- 1, 0 stopped early
- Disease areas
- Mental health
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Companies that need a new molecule because of this drug
3 company-target rows on route B and 3 company-target rows on route A because of this drug.
Companies on route B for this drug
In the product3 company-target rows are on route B because of Tedatioxetine.
See the 3 company-target rows on route B for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Companies on route A for this drug
In the product3 company-target rows are on route A because of Tedatioxetine.
See the 3 company-target rows on route A for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Targets
| Gene | Protein | UniProt |
|---|---|---|
| HTR3E | 5-hydroxytryptamine receptor 3E | A5X5Y0 |
| HTR3B | 5-hydroxytryptamine receptor 3B | O95264 |
| SLC6A2 | Sodium-dependent noradrenaline transporter | P23975 |
| HTR2A | 5-hydroxytryptamine receptor 2A | P28223 |
| HTR2C | 5-hydroxytryptamine receptor 2C | P28335 |
| SLC6A4 | Sodium-dependent serotonin transporter | P31645 |
| ADRA1A | Alpha-1A adrenergic receptor | P35348 |
| HTR3A | 5-hydroxytryptamine receptor 3A | P46098 |
| SLC6A3 | Sodium-dependent dopamine transporter | Q01959 |
| HTR3D | 5-hydroxytryptamine receptor 3D | Q70Z44 |
| HTR3C | 5-hydroxytryptamine receptor 3C | Q8WXA8 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase 2 | 1 | 1 | 0 | 0 |
| All trials | 1 |
Who ran its trials
| Company | Role | Years |
|---|---|---|
| Lundbeck | Lead sponsor of trials | 2007 to now |