Drug

Pumosetrag

As of the edition of 20 October 2026, Pumosetrag is a small molecule: went quiet in 2011; acts on HTR3A, HTR3B and HTR3C and 2 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2011
Kind
Small molecule
Registered trials
3, 0 stopped early
Disease areas
Digestive system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of Pumosetrag.

Targets

GeneProteinUniProt
HTR3E5-hydroxytryptamine receptor 3EA5X5Y0
HTR3B5-hydroxytryptamine receptor 3BO95264
HTR3A5-hydroxytryptamine receptor 3AP46098
HTR3D5-hydroxytryptamine receptor 3DQ70Z44
HTR3C5-hydroxytryptamine receptor 3CQ8WXA8

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 22200
Phase 31000
All trials3

Who ran its trials

CompanyRoleYears
Dynogen PharmaceuticalsLead sponsor of trials2005 to now
Edusa PharmaceuticalsLead sponsor of trials