Drug

NUV-422

As of the edition of 20 October 2026, NUV-422 is a drug known only by a code name: stopped in 2026; acts on CDK2, CDK4 and CDK6.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2026
Kind
Code name only
Registered trials
3, 3 stopped early
Disease areas
Cancer; Skin and connective tissue; Urinary and reproductive

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

3 company-target rows are on route A because of NUV-422.

Targets

GeneProteinUniProt
CDK4Cyclin-dependent kinase 4P11802
CDK2Cyclin-dependent kinase 2P24941
CDK6Cyclin-dependent kinase 6Q00534

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11001
Phase 22002
All trials3

Who ran its trials

CompanyRoleYears
Nuvation BioLead sponsor of trials2020 to now