Drug

Obatoclax

As of the edition of 20 October 2026, Obatoclax is a small molecule: stopped in 2018; acts on BCL2, BCL2A1 and BCL2L1 and 3 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2018
Kind
Small molecule
Registered trials
19, 8 stopped early
Disease areas
Cancer; Blood and lymph; Immune system; Lungs and airways; Heart and blood vessels; Infections

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

12 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

12 company-target rows are on route A because of Obatoclax.

Targets

GeneProteinUniProt
BCL2Apoptosis regulator Bcl-2P10415
BCL2L1Bcl-2-like protein 1Q07817
MCL1Induced myeloid leukemia cell differentiation protein Mcl-1Q07820
BCL2A1Bcl-2-related protein A1Q16548
BCL2L2Bcl-2-like protein 2Q92843
BCL2L10Bcl-2-like protein 10Q9HD36

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 15203
Phase 213904
Phase 31001
All trials19

Who ran its trials

CompanyRoleYears
Gemin XLead sponsor of trials2004 to now
TevaLead sponsor of trials2012 to now