Drug

Pelcitoclax

As of the edition of 20 October 2026, Pelcitoclax is a small molecule: stopped in 2026; acts on BCL2 and BCL2L1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2026
Kind
Small molecule
Registered trials
10, 5 stopped early
Disease areas
Cancer; Blood and lymph; Lungs and airways; Immune system; Pregnancy and women's health; Urinary and reproductive

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company-target row on route A because of this drug.

Companies on route A for this drug

In the product

1 company-target row is on route A because of Pelcitoclax.

Targets

GeneProteinUniProt
BCL2Apoptosis regulator Bcl-2P10415
BCL2L1Bcl-2-like protein 1Q07817

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 16123
Phase 24012
All trials10

Who ran its trials

CompanyRoleYears
Ascentage PharmaLead sponsor of trials2017 to now