Target

BCL2L1

Bcl-2-like protein 1

As of the edition of 20 October 2026, BCL2L1 (bcl-2-like protein 1, UniProt Q07817) has 7 drugs tested at it and 9 companies on the list, 6 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q07817
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
126
Disease areas
Cancer; Blood and lymph; Immune system; Lungs and airways; Hormones; Urinary and reproductive; Pregnancy and women's health; Eye
Registered trials of its drugs
83

Drugs at this target

StatusCount
Active2
Stopped3
Status not established2
Total7
DrugStatusFurthest phaseUS protection
NavitoclaxActivePhase 3none listed
ObatoclaxStoppedPhase 3none listed
PelcitoclaxStoppedPhase 2none listed
LP-118ActivePhase 2none listed
DT-2216StoppedPhase 2none listed
UBX1325Status not establishedPhase 2none listed
FoselutoclaxStatus not establishedPhase 2none listed

7 of 7 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A6
Engaged3
Total on the list9
Three companies on route A or B, with the route only
CompanyRoute
Ascentage PharmaRoute A
TevaRoute A
RocheRoute A

The other 6 companies at BCL2L1

In the product

9 companies in all; 6 are not named here, and no score is.

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