Probatebeta
Target

MAOA

Amine oxidase [flavin-containing] A

As of the edition of 20 October 2026, MAOA (amine oxidase [flavin-containing] A, UniProt P21397) has 14 drugs tested at it and 8 companies on the list, 2 on route A and 3 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P21397
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
4
Disease areas
Mental health; Cancer; Nervous system; Blood and lymph; Urinary and reproductive; Chemically induced; Heart and blood vessels; Hormones
Registered trials of its drugs
28

Drugs at this target

StatusCount
Marketed7
Went quiet1
Stopped1
Withdrawn from market5
Total14
DrugStatusFurthest phaseUS protection
TranylcypromineMarketedPhase 4none listed
PhenelzineMarketedPhase 4none listed
CX-157Went quietPhase 2none listed
IndantadolStoppedPhase 2none listed
MoclobemideMarketedPhase 3none listed
IsocarboxazidMarketedPhase 1none listed
IproniazidMarketedNo phase statednone listed
MebanazineWithdrawn from marketNo phase statednone listed
MinaprineWithdrawn from marketNo phase statednone listed
NialamideWithdrawn from marketNo phase statednone listed
PargylineMarketedNo phase statednone listed
PhenoxypropazineWithdrawn from marketNo phase statednone listed

12 of 14 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A2
Route B3
Undetermined3
Total on the list8
Three companies on route A or B, with the route only
CompanyRoute
PfizerRoute B
Advanz PharmaRoute B
GSKRoute B

The other 5 companies at MAOA

In the product

8 companies in all; 5 are not named here, and no score is.

See the 8 companies at MAOA, ranked, with the facts behind eachRequest access. Nothing is shown until you do.

Other targets in mental health

Companies holding approvals at MAOA