Company

Ligand Pharmaceuticals

As of the edition of 20 October 2026, Ligand Pharmaceuticals runs 11 drugs, 5 of them marketed; it is on route A at 2 targets and on route B at 0 targets.

Sources: ClinicalTrials.gov, FDA Orange Book and Purple Book, other approval registers, company records.

Family history

Ligand Pharmaceuticals was renamed in 1994.

The records place 5 company names in this family.

  • Ligand Pharmaceuticals: renamed in 1994
  • Neurogen Corporation: acquired in 2009; successor Ligand Pharmaceuticals
  • Pfenex, Inc: acquired in 2020; successor Ligand Pharmaceuticals
  • Apeiron Biologics: acquired

Drugs by status

StatusCount
Marketed5
Went quiet2
Stopped3
Withdrawn from market1
Total11

Marketed drugs and when their US protection ends

DrugUS protectionRoute B rows
Teriparatidenone listed3
Acyclovirnone listed0
Bexarotenenone listed6
Alitretinoinnone listed0
SparsentanEnds 2031 (exclusivity)2

A route B row is one company at one target.

Where it needs a new molecule

Route A at 2 targets, route B at 0 targets.

Three of its 2 rows, by target and route
TargetRoute
GCGR Glucagon receptorRoute A
DRD2 Dopamine receptor D2Route A

All 2 rows on route A or B

In the product

2 company-target rows on route A or B; 0 are not shown here, and no score is.

Where its trials are

  • Nutrition and metabolism: 8 trials led
  • Bones, joints and muscles: 4 trials led
  • Hormones: 3 trials led