Drug

AB-101

As of the edition of 20 October 2026, AB-101 is a drug: in active development; acts on ADRA1A, ADRA1B and ADRA1D.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2027
Kind
Unknown
Registered trials
7, 1 stopped early
Disease areas
Immune system; Skin and connective tissue; Cancer; Blood and lymph; Urinary and reproductive; Bones, joints and muscles

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

3 company-target rows are on route A because of AB-101.

Targets

GeneProteinUniProt
ADRA1DAlpha-1D adrenergic receptorP25100
ADRA1AAlpha-1A adrenergic receptorP35348
ADRA1BAlpha-1B adrenergic receptorP35368

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 14220
Phase 23111
All trials7

Who ran its trials

CompanyRoleYears
Applied BiologyLead sponsor of trials2018 to now
Artiva BiotherapeuticsLead sponsor of trials2021 to now
Arbutus BiopharmaLead sponsor of trials2023 to now
AffimedLead sponsor of trials2023 to now
IrisLead sponsor of trials2024 to now
Alphyn BiologicsLead sponsor of trials2025 to now