Drug

Apabetalone

As of the edition of 20 October 2026, Apabetalone is a small molecule: in active development; acts on BRD2, BRD3 and BRD4 and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2025
Kind
Small molecule
Registered trials
12, 3 stopped early
Disease areas
Heart and blood vessels; Nutrition and metabolism; Lungs and airways; Hormones; Infections; Pregnancy and women's health

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
BRD4Bromodomain-containing protein 4O60885
BRD2Bromodomain-containing protein 2P25440
BRD3Bromodomain-containing protein 3Q15059
BRDTBromodomain testis-specific proteinQ58F21

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 28512
Phase 33111
All trials12

Who ran its trials

CompanyRoleYears
ResverlogixLead sponsor of trials2008 to now