Drug

Molibresib

As of the edition of 20 October 2026, Molibresib is a small molecule: stopped in 2021; acts on BRD2, BRD3 and BRD4 and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2021
Kind
Small molecule
Registered trials
9, 5 stopped early
Disease areas
Cancer; Blood and lymph; Immune system; Heart and blood vessels; Lungs and airways; Digestive system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of Molibresib.

Targets

GeneProteinUniProt
BRD4Bromodomain-containing protein 4O60885
BRD2Bromodomain-containing protein 2P25440
BRD3Bromodomain-containing protein 3Q15059
BRDTBromodomain testis-specific proteinQ58F21

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1000
Phase 15203
Phase 23102
All trials9

Who ran its trials

CompanyRoleYears
GSKLead sponsor of trials