BRD2
Bromodomain-containing protein 2
As of the edition of 20 October 2026, BRD2 (bromodomain-containing protein 2, UniProt P25440) has 6 drugs tested at it and 7 companies on the list, 3 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P25440
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- Inside the cell
- Solved structures
- 177
- Disease areas
- Cancer; Blood and lymph; Heart and blood vessels; Immune system; Lungs and airways; Nutrition and metabolism; Skin and connective tissue; Hormones
- Registered trials of its drugs
- 48
Drugs at this target
| Status | Count |
|---|---|
| Active | 3 |
| Went quiet | 1 |
| Stopped | 2 |
| Total | 6 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Apabetalone | Active | Phase 3 | none listed |
| Pelabresib | Active | Phase 3 | none listed |
| Molibresib | Stopped | Phase 2 | none listed |
| Birabresib | Stopped | Phase 2 | none listed |
| RO-6870810 | Went quiet | Phase 1 | none listed |
| Ezobresib | Active | Phase 2 | none listed |
6 of 6 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 3 |
| Engaged | 4 |
| Total on the list | 7 |
| Company | Route |
|---|---|
| GSK | Route A |
| Merck & Co. | Route A |
| Roche | Route A |
The other 4 companies at BRD2
In the product7 companies in all; 4 are not named here, and no score is.
See the 7 companies at BRD2, ranked, with the facts behind eachRequest access. Nothing is shown until you do.