Drug

AT-9283

As of the edition of 20 October 2026, AT-9283 is a small molecule: went quiet in 2015; acts on ABL1, AURKA and AURKB and 3 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2015
Kind
Small molecule
Registered trials
2, 1 stopped early
Disease areas
Blood and lymph; Cancer; Immune system; Heart and blood vessels

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company-target row on route B and 5 company-target rows on route A because of this drug.

Companies on route B for this drug

In the product

1 company-target row is on route B because of AT-9283.

Companies on route A for this drug

In the product

5 company-target rows are on route A because of AT-9283.

Targets

GeneProteinUniProt
AURKAAurora kinase AO14965
JAK2Tyrosine-protein kinase JAK2O60674
ABL1Tyrosine-protein kinase ABL1P00519
FLT3Receptor-type tyrosine-protein kinase FLT3P36888
JAK3Tyrosine-protein kinase JAK3P52333
AURKBAurora kinase BQ96GD4

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 22101
All trials2

Who ran its trials

CompanyRoleYears
OtsukaLead sponsor of trials2006 to now