Drug

CYC-116

As of the edition of 20 October 2026, CYC-116 is a small molecule: stopped in 2009; acts on AURKA, AURKB and AURKC and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2009
Kind
Small molecule
Registered trials
1, 1 stopped early

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of CYC-116.

Targets

GeneProteinUniProt
AURKAAurora kinase AO14965
KDRVascular endothelial growth factor receptor 2P35968
AURKBAurora kinase BQ96GD4
AURKCAurora kinase CQ9UQB9

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11001
All trials1

Who ran its trials

CompanyRoleYears
Cyclacel PharmaceuticalsLead sponsor of trials2007 to now