Drug

Danusertib

As of the edition of 20 October 2026, Danusertib is a small molecule: went quiet in 2011; acts on AURKA, AURKB and AURKC.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2011
Kind
Small molecule
Registered trials
3, 1 stopped early
Disease areas
Blood and lymph; Cancer; Heart and blood vessels; Immune system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

3 company-target rows are on route A because of Danusertib.

Targets

GeneProteinUniProt
AURKAAurora kinase AO14965
AURKBAurora kinase BQ96GD4
AURKCAurora kinase CQ9UQB9

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 23101
All trials3

Who ran its trials

CompanyRoleYears
Nerviano Medical SciencesLead sponsor of trials2007 to now