Drug

Dinaciclib

As of the edition of 20 October 2026, Dinaciclib is a small molecule: stopped in 2022; acts on CDK1, CDK2 and CDK5 and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2022
Kind
Small molecule
Registered trials
18, 5 stopped early
Disease areas
Cancer; Blood and lymph; Immune system; Skin and connective tissue; Heart and blood vessels; Digestive system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

8 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

8 company-target rows are on route A because of Dinaciclib.

Targets

GeneProteinUniProt
CDK1Cyclin-dependent kinase 1P06493
CDK2Cyclin-dependent kinase 2P24941
CDK9Cyclin-dependent kinase 9P50750
CDK5Cyclin-dependent kinase 5Q00535

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 110712
Phase 27313
Phase 31100
All trials18

Who ran its trials

CompanyRoleYears
Merck & Co.Lead sponsor of trials2006 to now
AbbVieLead sponsor of trials2018 to now