Drug

RG-547

As of the edition of 20 October 2026, RG-547 is a small molecule: went quiet in 2008; acts on CDK1, CDK2 and CDK4.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2008
Kind
Small molecule
Registered trials
1, 0 stopped early
Disease areas
Cancer

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of RG-547.

Targets

GeneProteinUniProt
CDK1Cyclin-dependent kinase 1P06493
CDK4Cyclin-dependent kinase 4P11802
CDK2Cyclin-dependent kinase 2P24941

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
All trials1

Who ran its trials

CompanyRoleYears
RocheLead sponsor of trials2005 to now