Drug

RGB-286638

As of the edition of 20 October 2026, RGB-286638 is a small molecule: stopped in 2015; acts on CDK1, CDK2 and CDK4 and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2015
Kind
Small molecule
Registered trials
1, 1 stopped early
Disease areas
Blood and lymph; Cancer

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of RGB-286638.

Targets

GeneProteinUniProt
CDK1Cyclin-dependent kinase 1P06493
CDK4Cyclin-dependent kinase 4P11802
CDK2Cyclin-dependent kinase 2P24941
CDK9Cyclin-dependent kinase 9P50750

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11001
All trials1

Who ran its trials

CompanyRoleYears
AgennixLead sponsor of trials2011 to now