Drug

Metaraminol

As of the edition of 20 October 2026, Metaraminol is a small molecule: marketed, first approved in 1987 (US); acts on ADRA1A, ADRA1B and ADRA1D; no US protection is listed.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Marketed; latest approval 1987
Kind
Small molecule
Brand name
Aramine
First approved
22 December 1987 (US)
Approvals on record
1 in 1 region
Holder of the most recent approval
Merck & Co.
Registered trials
4, 1 stopped early
Disease areas
Heart and blood vessels; Pregnancy and women's health; Urinary and reproductive

US protection

No US protection is listed.

The FDA registers list no drug-substance patent or exclusivity that counts for this drug.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route B because of this drug.

Companies on route B for this drug

In the product

3 company-target rows are on route B because of Metaraminol.

Targets

GeneProteinUniProt
ADRA1DAlpha-1D adrenergic receptorP25100
ADRA1AAlpha-1A adrenergic receptorP35348
ADRA1BAlpha-1B adrenergic receptorP35368

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1000
Phase 21100
Phase 31001
Phase 41100
All trials4

Who has held its approvals

CompanyRoleYears
Merck & Co.Applicant1987 to now