Drug

PEN-866

As of the edition of 20 October 2026, PEN-866 is a small molecule: stopped in 2026; acts on HSP90AA1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2026
Kind
Small molecule
Registered trials
2, 0 stopped early
Disease areas
Cancer; Digestive system; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company on route A because of this drug.

Companies on route A for this drug

In the product

1 company is on route A because of PEN-866.

Target

GeneProteinUniProt
HSP90AA1Heat shock protein HSP 90-alphaP07900

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 22000
All trials2

Who ran its trials

CompanyRoleYears
Tarveda TherapeuticsLead sponsor of trials2017 to now