Drug

Tozadenant

As of the edition of 20 October 2026, Tozadenant is a small molecule: stopped in 2018; acts on ADORA2A.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2018
Kind
Small molecule
Registered trials
7, 4 stopped early
Disease areas
Nervous system; Digestive system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company on route A because of this drug.

Companies on route A for this drug

In the product

1 company is on route A because of Tozadenant.

Target

GeneProteinUniProt
ADORA2AAdenosine receptor A2aP29274

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 13102
Phase 21100
Phase 33102
All trials7

Who ran its trials

CompanyRoleYears
Biotie TherapiesLead sponsor of trials2008 to now