Drug

Etrumadenant

As of the edition of 20 October 2026, Etrumadenant is a small molecule: in active development; acts on ADORA2A and ADORA2B.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2029
Kind
Small molecule
Registered trials
22, 3 stopped early
Disease areas
Cancer; Lungs and airways; Urinary and reproductive; Digestive system; Hormones; Pregnancy and women's health

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of Etrumadenant.

Targets

GeneProteinUniProt
ADORA2AAdenosine receptor A2aP29274
ADORA2BAdenosine receptor A2bP29275

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 18701
Phase 214482
All trials22

Who ran its trials

CompanyRoleYears
RocheLead sponsor of trials2017 to now
Arcus BiosciencesLead sponsor of trials2018 to now
Coherus OncologyLead sponsor of trials2022 to now
Gilead SciencesLead sponsor of trials2023 to now