AURKC
Aurora kinase C
As of the edition of 20 October 2026, AURKC (aurora kinase C, UniProt Q9UQB9) has 8 drugs tested at it and 6 companies on the list, 5 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- Q9UQB9
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- Inside the cell
- Solved structures
- 3
- Disease areas
- Cancer; Blood and lymph; Immune system; Digestive system; Heart and blood vessels; Hormones; Lungs and airways
- Registered trials of its drugs
- 19
Drugs at this target
| Status | Count |
|---|---|
| Went quiet | 2 |
| Stopped | 6 |
| Total | 8 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Tozasertib | Stopped | Phase 2 | none listed |
| Ilorasertib | Stopped | Phase 2 | none listed |
| Danusertib | Went quiet | Phase 2 | none listed |
| Cenisertib | Stopped | Phase 1 | none listed |
| CYC-116 | Stopped | Phase 1 | none listed |
| MK-6592 | Stopped | Phase 1 | none listed |
| SNS-314 | Went quiet | Phase 1 | none listed |
| TTP-607 | Stopped | Phase 1 | none listed |
8 of 8 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 5 |
| Engaged | 1 |
| Total on the list | 6 |
| Company | Route |
|---|---|
| Merck & Co. | Route A |
| Merck KGaA | Route A |
| Cyclacel Pharmaceuticals | Route A |
The other 3 companies at AURKC
In the product6 companies in all; 3 are not named here, and no score is.
See the 6 companies at AURKC, ranked, with the facts behind eachRequest access. Nothing is shown until you do.