Target

PTGDR2

Prostaglandin D2 receptor 2

As of the edition of 20 October 2026, PTGDR2 (prostaglandin D2 receptor 2, UniProt Q9Y5Y4) has 14 drugs tested at it and 12 companies on the list, 12 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q9Y5Y4
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
6
Disease areas
Lungs and airways; Immune system; Ear, nose and throat; Blood and lymph; Skin and connective tissue; Infections; Inherited and neonatal; Cancer
Registered trials of its drugs
73

Drugs at this target

StatusCount
Went quiet11
Stopped3
Total14
DrugStatusFurthest phaseUS protection
FevipiprantStoppedPhase 3none listed
AZD1981Went quietPhase 2none listed
TimapiprantWent quietPhase 2none listed
BI-671800Went quietPhase 2none listed
MK-1029Went quietPhase 2none listed
SetipiprantWent quietPhase 2none listed
QAV680StoppedPhase 2none listed
ADC3680Went quietPhase 2none listed
BI 1021958Went quietPhase 1none listed
VidupiprantWent quietPhase 2none listed
ARRY-502Went quietPhase 2none listed
RamatrobanStoppedPhase 3none listed

12 of 14 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A12
Total on the list12
Three companies on route A or B, with the route only
CompanyRoute
NovartisRoute A
Merck & Co.Route A
AbbVieRoute A

The other 9 companies at PTGDR2

In the product

12 companies in all; 9 are not named here, and no score is.

See the 12 companies at PTGDR2, ranked, with the facts behind eachRequest access. Nothing is shown until you do.