Target

ADORA3

Adenosine receptor A3

As of the edition of 20 October 2026, ADORA3 (adenosine receptor A3, UniProt P0DMS8) has 6 drugs tested at it and 16 companies on the list, 0 on route A and 4 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P0DMS8
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
5
Disease areas
Lungs and airways; Heart and blood vessels; Nervous system; Urinary and reproductive; Immune system; Nutrition and metabolism; Pregnancy and women's health; Mental health
Registered trials of its drugs
443

Drugs at this target

StatusCount
Marketed4
Active2
Total6
DrugStatusFurthest phaseUS protection
CaffeineMarketedPhase 4none listed
Theophylline anhydrousMarketedPhase 4none listed
AdenosineMarketedPhase 4none listed
PiclidenosonActivePhase 3none listed
NamodenosonActivePhase 3none listed
Theophylline glycinateMarketedNo phase statednone listed

6 of 6 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route B4
Engaged4
Undetermined8
Total on the list16
Three companies on route A or B, with the route only
CompanyRoute
SanofiRoute B
Aralez PharmaceuticalsRoute B
NobelpharmaRoute B

The other 13 companies at ADORA3

In the product

16 companies in all; 13 are not named here, and no score is.

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