ADORA2B
Adenosine receptor A2b
As of the edition of 20 October 2026, ADORA2B (adenosine receptor A2b, UniProt P29275) has 7 drugs tested at it and 14 companies on the list, 2 on route A and 5 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P29275
- How well studied
- Drug target: an approved drug acts on it
- Where it sits in the cell
- At a membrane
- Solved structures
- 5
- Disease areas
- Lungs and airways; Urinary and reproductive; Heart and blood vessels; Nervous system; Cancer; Pregnancy and women's health; Digestive system; Immune system
- Registered trials of its drugs
- 566
Drugs at this target
| Status | Count |
|---|---|
| Marketed | 5 |
| Active | 1 |
| Status not established | 1 |
| Total | 7 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Caffeine | Marketed | Phase 4 | none listed |
| Pentoxifylline | Marketed | Phase 4 | none listed |
| Theophylline anhydrous | Marketed | Phase 4 | none listed |
| Adenosine | Marketed | Phase 4 | none listed |
| Etrumadenant | Active | Phase 2 | none listed |
| PBF-1129 | Status not established | Phase 1 | none listed |
| Theophylline glycinate | Marketed | No phase stated | none listed |
7 of 7 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 2 |
| Route B | 5 |
| Engaged | 5 |
| Undetermined | 2 |
| Total on the list | 14 |
| Company | Route |
|---|---|
| Sanofi | Route B |
| Validus Pharmaceuticals | Route B |
| Roche | Route A |
The other 11 companies at ADORA2B
In the product14 companies in all; 11 are not named here, and no score is.
See the 14 companies at ADORA2B, ranked, with the facts behind eachRequest access. Nothing is shown until you do.