US protection ending in 2029: Ear, nose and throat
As of the edition of 20 October 2026, 11 drugs have US protection that ends in 2029 in ear, nose and throat; 8 of them have at least one company on route B because of it.
Sources: FDA Orange Book and Purple Book, other approval registers.
11 drugs
| Drug | US protection | Status | Holder | Target | Route B rows |
|---|---|---|---|---|---|
| Amifampridine | Ends 2029 (exclusivity) | Marketed | Angelini Pharma | 0 | |
| Atezolizumab | Ends 2029 (orphan exclusivity) | Marketed | Roche | CD274 | 1 |
| Avelumab | Ends 2029 (computed from the first US licence) | Marketed | Merck KGaA | CD274 | 1 |
| Azacitidine | Ends 2029 (exclusivity) | Marketed | Bristol Myers Squibb | DNMT1, DNMT3A | 4 |
| Budesonide | Ends 2029 (exclusivity) | Marketed | NR3C1 | 5 | |
| Crizotinib | Ends 2029 (patent) | Marketed | Pfizer | ALK, MET, ROS1 | 2 |
| Edaravone | Ends 2029 (exclusivity) | Marketed | Shionogi | 0 | |
| Infigratinib | Ends 2029 (patent) | Marketed | Helsinn Healthcare | FGFR1, FGFR2, FGFR3 | 4 |
| Lapatinib | Ends 2029 (patent) | Marketed | Novartis | EGFR | 2 |
| Nitric oxide | Ends 2029 (patent) | Marketed | Byk-Mallinckrodt CIL | GUCY1B1, GUCY1B2 | 4 |
| Posaconazole | Ends 2029 (exclusivity) | Marketed | Merck & Co. | 0 |
Listed by name. A route B row is one company at one target; for a drug with one target that is the number of companies. US protection is the US only, and it is not the date generics or biosimilars can enter.
Which companies are on route B in 2029 in ear, nose and throat
In the product8 of these 11 drugs have at least one company on route B. Which companies, and their scores, are in the product.
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