ADH5
Alcohol dehydrogenase class-3
As of the edition of 20 October 2026, ADH5 (alcohol dehydrogenase class-3, UniProt P11766) has 3 drugs tested at it and 2 companies on the list, 0 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P11766
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- Inside the cell
- Solved structures
- 10
- Disease areas
- Lungs and airways; Digestive system; Inherited and neonatal; Immune system
- Registered trials of its drugs
- 12
Drugs at this target
| Status | Count |
|---|---|
| Active | 1 |
| Went quiet | 1 |
| Withdrawn from market | 1 |
| Total | 3 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Cavosonstat | Active | Phase 2 | none listed |
| N6022 | Went quiet | Phase 2 | none listed |
| Nitrefazole | Withdrawn from market | No phase stated | none listed |
3 of 3 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Engaged | 1 |
| Undetermined | 1 |
| Total on the list | 2 |