Target

CA12

Carbonic anhydrase 12

As of the edition of 20 October 2026, CA12 (carbonic anhydrase 12, UniProt O43570) has 3 drugs tested at it and 5 companies on the list, 1 on route A and 1 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
O43570
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
40
Disease areas
Lungs and airways; Nervous system; Heart and blood vessels; Nutrition and metabolism; Eye; Inherited and neonatal; Mental health; Hormones
Registered trials of its drugs
91

Drugs at this target

StatusCount
Marketed2
Stopped1
Total3
DrugStatusFurthest phaseUS protection
AcetazolamideMarketedPhase 4none listed
SLC-0111StoppedPhase 2none listed
DichlorphenamideMarketedPhase 3none listed

3 of 3 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Route B1
Undetermined3
Total on the list5
Three companies on route A or B, with the route only
CompanyRoute
União Química Farmacêutica Nacional S/ARoute B
Welichem BiotechRoute A

The other 3 companies at CA12

In the product

5 companies in all; 3 are not named here, and no score is.

See the 5 companies at CA12, ranked, with the facts behind eachRequest access. Nothing is shown until you do.