MAPK8
Mitogen-activated protein kinase 8
As of the edition of 20 October 2026, MAPK8 (mitogen-activated protein kinase 8, UniProt P45983) has 3 drugs tested at it and 2 companies on the list, 2 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P45983
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- Inside the cell
- Solved structures
- 41
- Disease areas
- Lungs and airways; Blood and lymph; Cancer; Digestive system; Pregnancy and women's health; Urinary and reproductive
- Registered trials of its drugs
- 12
Drugs at this target
| Status | Count |
|---|---|
| Went quiet | 1 |
| Stopped | 2 |
| Total | 3 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| CC-90001 | Stopped | Phase 2 | none listed |
| Bentamapimod | Went quiet | Phase 2 | none listed |
| CC-401 | Stopped | Phase 1 | none listed |
3 of 3 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 2 |
| Total on the list | 2 |
| Company | Route |
|---|---|
| Bristol Myers Squibb | Route A |
| PregLem | Route A |
The other 0 companies at MAPK8
In the product2 companies in all; 0 are not named here, and no score is.
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