US protection ending in 2029: Blood and lymph
As of the edition of 20 October 2026, 31 drugs have US protection that ends in 2029 in blood and lymph; 18 of them have at least one company on route B because of it.
Sources: FDA Orange Book and Purple Book, other approval registers.
31 drugs
| Drug | US protection | Status | Holder | Target | Route B rows |
|---|---|---|---|---|---|
| Afatinib | Ends 2029 (patent) | Marketed | Boehringer Ingelheim | EGFR | 1 |
| Atazanavir | Ends 2029 (patent) | Marketed | Bristol Myers Squibb | 0 | |
| Atezolizumab | Ends 2029 (orphan exclusivity) | Marketed | Roche | CD274 | 1 |
| Avelumab | Ends 2029 (computed from the first US licence) | Marketed | Merck KGaA | CD274 | 1 |
| Azacitidine | Ends 2029 (exclusivity) | Marketed | Bristol Myers Squibb | DNMT1, DNMT3A | 4 |
| Bendamustine | Ends 2029 (patent) | Marketed | Teva | 0 | |
| Brentuximab vedotin | Ends 2029 (orphan exclusivity) | Marketed | Pfizer | TNFRSF8, TUBB, TUBB1 | 10 |
| Budesonide | Ends 2029 (exclusivity) | Marketed | NR3C1 | 5 | |
| Crizotinib | Ends 2029 (patent) | Marketed | Pfizer | ALK, MET, ROS1 | 2 |
| Dapagliflozin | Ends 2029 (patent) | Marketed | AstraZeneca | SLC5A2 | 2 |
| Emicizumab | Ends 2029 (computed from the first US licence) | Marketed | Roche | F10, F9 | 2 |
| Etonogestrel | Ends 2029 (exclusivity) | Marketed | Organon | PGR | 1 |
| Ferric derisomaltose | Ends 2029 (patent) | Marketed | Pharmacosmos | TF | 2 |
| Ferric pyrophosphate citrate | Ends 2029 (patent) | Marketed | Rockwell Medical | 0 | |
| Florbetaben | Ends 2029 (patent) | Marketed | Lantheus Biosciences | 0 | |
| Gemtuzumab ozogamicin | Ends 2029 (computed from the first US licence) | Marketed | Pfizer | CD33 | 0 |
| Infigratinib | Ends 2029 (patent) | Marketed | Helsinn Healthcare | FGFR1, FGFR2, FGFR3 | 4 |
| Ixazomib citrate | Ends 2029 (patent) | Marketed | Takeda | PSMB5 | 0 |
| Lapatinib | Ends 2029 (patent) | Marketed | Novartis | EGFR | 2 |
| Lurbinectedin | Ends 2029 (patent) | Marketed | Jazz Pharmaceuticals | 0 | |
| Nitric oxide | Ends 2029 (patent) | Marketed | Byk-Mallinckrodt CIL | GUCY1B1, GUCY1B2 | 4 |
| Nonacog beta pegol | Ends 2029 (computed from the first US licence) | Marketed | Novo Nordisk | 0 | |
| Ocrelizumab | Ends 2029 (computed from the first US licence) | Marketed | Roche | MS4A1 | 0 |
| Oxymorphone | Ends 2029 (patent) | Marketed | Endo | OPRD1, OPRK1, OPRM1 | 0 |
| Phenobarbital | Ends 2029 (exclusivity) | Marketed | SUN Pharmaceutical Industries | 0 | |
| Posaconazole | Ends 2029 (exclusivity) | Marketed | Merck & Co. | 0 | |
| Ruxolitinib | Ends 2029 (exclusivity) | Marketed | JAK1, JAK2 | 4 | |
| Sarilumab | Ends 2029 (computed from the first US licence) | Marketed | Sanofi | IL6R | 1 |
| Tisagenlecleucel | Ends 2029 (orphan exclusivity) | Marketed | Novartis | CD19 | 1 |
| Trazodone | Ends 2029 (patent) | Marketed | Pragma Pharmaceuticals | HTR2A, HTR2C | 1 |
| Varicella zoster virus envelope glycoprotein e | Ends 2029 (computed from the first US licence) | Marketed | GSK | 0 |
Listed by name. A route B row is one company at one target; for a drug with one target that is the number of companies. US protection is the US only, and it is not the date generics or biosimilars can enter.
Which companies are on route B in 2029 in blood and lymph
In the product18 of these 31 drugs have at least one company on route B. Which companies, and their scores, are in the product.
Get this list with the companies, scores and sources as a fileRequest access. Nothing is shown until you do.